Recording of spontaneous vagus nerve activity during Pentylenetetrazol-induced seizures in rats
نویسندگان
چکیده
منابع مشابه
Effect of berberine on pentylenetetrazol-induced seizures in rats
Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...
متن کاملVagus nerve activity based prediction of epileptic seizures in rats
Continuous open loop vagus nerve stimulation (VNS) is an option for the treatment of refractory epilepsy. Animal studies have shown that VNS is able to shorten or even abolish ongoing seizures and that stimulation prior to a pending seizure may prevent the seizure from occurring. VNS therapy might therefore be improved by close loop stimulation, but seizures must then be predicted or detected. ...
متن کاملMontelukast Inhibits Pentylenetetrazol-Induced Seizures in Rats
BACKGROUND Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in pentylenetetrazol (PTZ)-induced seizures in rats. MATERIAL AND METHODS Of the 48 male Sprague-Dawley rats used in the study, 24 were assigned to EEG recordings (group A) and 24 were ...
متن کاملEffect of berberine on pentylenetetrazol-induced seizures in rats
Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...
متن کاملeffect of berberine on pentylenetetrazol-induced seizures in rats
objective: antiepileptic drugs (aeds) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current aeds therapy. some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. the aim of the p...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Methods
سال: 2020
ISSN: 0165-0270
DOI: 10.1016/j.jneumeth.2020.108832